Limbic changes identified by imaging in bipolar patients.

  title={Limbic changes identified by imaging in bipolar patients.},
  author={Paolo Brambilla and John P. Hatch and Jair C. Soares},
  journal={Current psychiatry reports},
  volume={10 6},
The hippocampus and amygdala are key limbic regions for memory formation and emotion modulation that are potentially involved in the cognitive and affective symptoms of bipolar disorder. Here we discuss the most consistent MRI literature in bipolar disorder, focusing on the role of the hippocampus and amygdala. In child and adolescent patients, a unique pattern of abnormalities has begun to emerge, with volume deficits in the hippocampus and amygdala already detectable early in the illness… CONTINUE READING

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