Limbic and Corpus Callosum Aberrations in Adolescents with Bipolar Disorder: A Tract-Based Spatial Statistics Analysis

@article{BarneaGoraly2009LimbicAC,
  title={Limbic and Corpus Callosum Aberrations in Adolescents with Bipolar Disorder: A Tract-Based Spatial Statistics Analysis},
  author={Naama Barnea-Goraly and Kiki D. Chang and Asya Karchemskiy and Meghan E Howe and Allan L. Reiss},
  journal={Biological Psychiatry},
  year={2009},
  volume={66},
  pages={238-244}
}
BACKGROUND Bipolar disorder (BD) is a common and debilitating condition, often beginning in adolescence. Converging evidence from genetic and neuroimaging studies indicates that white matter abnormalities may be involved in BD. In this study, we investigated white matter structure in adolescents with familial bipolar disorder using diffusion tensor imaging (DTI) and a whole brain analysis. METHODS We analyzed DTI images using tract-based spatial statistics (TBSS), a whole-brain voxel-by-voxel… CONTINUE READING
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