Limb remote ischemic postconditioning protects cerebral ischemia from injury associated with expression of HIF-1α in rats

@inproceedings{Zong2015LimbRI,
  title={Limb remote ischemic postconditioning protects cerebral ischemia from injury associated with expression of HIF-1α in rats},
  author={Yonghua Zong and Ling Jiang and Mingxiao Zhang and Fangfang Zhou and Wenqian Qi and Shuai Li and Huijun Yang and Yu Pei Zou and Qingjie Xia and Xue Dong Zhou and Xiaosong Hu and Ting-Hua Wang},
  booktitle={BMC Neuroscience},
  year={2015}
}
Limb remote ischemic postconditioning (LRIP) can ameliorate cerebral ischemia–reperfusion injury (IRI), while the underlying mechanism remains elusive. Hypoxia-inducible factor 1α (HIF-1α) is an important transcription factor during cerebral ischemia damage. However, whether the neuroprotective effect of LRIP could be associated with HIF-1α is somewhat unclear. Here we tested the hypothesis that Limb remote ischemic postconditioning (LRIP) protecting brain from injury in middle cerebral artery… CONTINUE READING
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