Limb development: Marginal Fringe benefits

@article{Blair1997LimbDM,
  title={Limb development: Marginal Fringe benefits},
  author={Seth S Blair},
  journal={Current Biology},
  year={1997},
  volume={7},
  pages={R686-R690}
}
Recent results show that in the developing Drosophila wing, the secreted pioneer protein Fringe regulates the sensitivity of the Notch signaling pathway to different ligands. This provides a likely mechanism by which Fringe-like molecules may control patterning in both Drosophila and vertebrates. 

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A family of mammalian fringe genes implicated in boundary determination and the Notch pathway

  • SH Johnson, C Rauskolb, R Wilson, B Prabhakaran, KD Irvine, TF Vogt
  • Development
  • 1997

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