Ligustrazini inhibits endotoxin induced PAI-1 expression in human umbilical vein endothelial cells

Abstract

Plasminogen activator inhibitor 1 (PAI-1) is one of important coagulant factors. Endotoxin lipopolysaccharide (LPS) induces thrombosis by stimulating PAI-1 secretion of vascular cells (EC). Using sandwich enzyme-linked immunosorbent assay (ELISA) and Northern blot, was investigated the effects of Chinese medicine ligustrazini on PAI-1 expression in EC and… (More)
DOI: 10.1007/BF02888023

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