Lignans are involved in the antitumor activity of wheat bran in colon cancer SW480 cells.

@article{Qu2005LignansAI,
  title={Lignans are involved in the antitumor activity of wheat bran in colon cancer SW480 cells.},
  author={Hongyan Qu and Ronald L. Madl and Dolores J. Takemoto and Richard Carleton Baybutt and Weiqun Wang},
  journal={The Journal of nutrition},
  year={2005},
  volume={135 3},
  pages={598-602}
}
Wheat bran was shown to provide protection against colorectal cancer in human intervention and animal studies. Our recent study showed, however, that antitumor activities of wheat bran from various wheat cultivars differed significantly even when wheat fiber was equal in diets. We hypothesized that phytochemical lignans in wheat bran may account for the differences among wheat cultivars in cancer prevention. The concentration of a major lignan, secoisolariciresinol diglycoside, was determined… CONTINUE READING
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