Light transmittance as an index of cell volume in hippocampal slices: optical differences of interfaced and submerged positions.

@article{Kreisman1995LightTA,
  title={Light transmittance as an index of cell volume in hippocampal slices: optical differences of interfaced and submerged positions.},
  author={Norman R Kreisman and Joseph C. LaManna and Stehen Shaoyi Liao and E R Yeh and Josefina Alcala},
  journal={Brain research},
  year={1995},
  volume={693 1-2},
  pages={179-86}
}
Light transmittance (T) in the CA1 region of hippocampal slices was measured during exposure to media of various osmolarities to determine the utility of optical measurements as an index of changes in cell volume. In slices positioned at the gas-liquid interface, hypo-osmotic medium consistently produced a decrease in T and hyperosmotic medium produced an increase in T. The magnitude of deltaT was graded as a function of the strength of osmotic change. All changes in T were reversible upon… CONTINUE READING

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