Light therapy and supplementary Riboflavin in the SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis (FALS).

@article{Moges2009LightTA,
  title={Light therapy and supplementary Riboflavin in the SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis (FALS).},
  author={Helina Moges and Olavo M. Vasconcelos and William W. Campbell and Rosemary C Borke and Jennifer Anne McCoy and Lauren Kaczmarczyk and Ji Feng and Juanita J Anders},
  journal={Lasers in surgery and medicine},
  year={2009},
  volume={41 1},
  pages={52-9}
}
BACKGROUND AND OBJECTIVE Familial amyotrophic lateral sclerosis (FALS) is a neurodegenerative disease characterized by progressive loss of motor neurons and death. Mitochondrial dysfunction and oxidative stress play an important role in motor neuron loss in ALS. Light therapy (LT) has biomodulatory effects on mitochondria. Riboflavin improves energy efficiency in mitochondria and reduces oxidative injury. The purpose of this study was to examine the synergistic effect of LT and riboflavin on… CONTINUE READING

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