Light-responsive control of bacterial gene expression: precise triggering of the lac promoter activity using photocaged IPTG.

Abstract

Light can be used to control numerous cellular processes including protein function and interaction as well as gene expression in a non-invasive fashion and with unprecedented spatiotemporal resolution. However, for chemical phototriggers tight, gradual, and homogeneous light response has never been attained in living cells. Here, we report on a light… (More)
DOI: 10.1039/c4ib00027g

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@article{Binder2014LightresponsiveCO, title={Light-responsive control of bacterial gene expression: precise triggering of the lac promoter activity using photocaged IPTG.}, author={Dennis Binder and Alexander Gr{\"u}nberger and Anita Loeschcke and Christopher Probst and Claus Bier and J{\"o}rg Pietruszka and Wolfgang Wiechert and Dietrich Kohlheyer and Karl-Erich Jaeger and Thomas Drepper}, journal={Integrative biology : quantitative biosciences from nano to macro}, year={2014}, volume={6 8}, pages={755-65} }