Light-regulated, tissue-specific immunophilins in a higher plant.

@article{Luan1994LightregulatedTI,
  title={Light-regulated, tissue-specific immunophilins in a higher plant.},
  author={Shuang Luan and Mark W. Albers and Stuart L. Schreiber},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1994},
  volume={91 3},
  pages={
          984-8
        }
}
In addition to their application in organ transplantation, immunosuppressive drugs are valuable tools for studying signal transduction in eukaryotic cells. Using affinity chromatography, we have purified immunosuppressive drug receptors (immunophilins) from fava bean. Proteins belonging to both major classes of the immunophilin family identified from animal sources [FK506- and rapamycin-binding proteins (FKBPs) and cyclophilins] were present in this higher plant. FKBP13, the most abundant FKBP… CONTINUE READING

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