Light microscopic study of degenerating cobalt-filled optic axons in goldfish: role of microglia and radial glia in debris removal.

@article{Springer1989LightMS,
  title={Light microscopic study of degenerating cobalt-filled optic axons in goldfish: role of microglia and radial glia in debris removal.},
  author={Alan D Springer and Bryan R. Wilson},
  journal={The Journal of comparative neurology},
  year={1989},
  volume={282 1},
  pages={119-32}
}
Labeling severed axons with cobaltous-lysine ultimately leads to the degeneration of their distal segments. The present study was designed to determine whether microglia and radial glia have comparable roles in the elimination of degenerating axons. Another purpose was to determine whether the cobalt could escape from degenerating axons and enter intact neuronal cells. Optic axons were filled with cobaltous-lysine for 1 day and the retinal projections were examined from 1 to 106 days later… CONTINUE READING

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