Light-induced stimulation of retinal dopamine: a dose-response relationship.

  title={Light-induced stimulation of retinal dopamine: a dose-response relationship.},
  author={George C. Brainard and William W. Morgan},
  journal={Brain research},
  volume={424 1},
Light stimulates dopamine (DA) release in the retina. The purpose of this study was to determine the threshold and dose-response relationship between ocular light exposure and retinal DA synthesis in vivo. Groups of dark-adapted rats were exposed to 0, 1, 3, 5, 10, 25, 50, 100 or 1000 microwatts per square centimeter (microW/cm2) of white light for 15 min. Retinal DA and dihydroxyphenylalanine (DOPA) were subsequently quantified by liquid chromatography with electrochemical detection. Both the… CONTINUE READING

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