Light induced retinal degeneration activates a caspase-independent pathway involving cathepsin D.


Neuroprotection strategies in the retina aim at interference with regulatory mechanisms of cell death. To successfully target these mechanisms it is necessary to understand the molecular pathways activated in the degenerating retina. Induced retinal degeneration models, like the light damage model, give a synchronized response allowing their detailed… (More)
DOI: 10.1016/j.neuint.2010.06.006