Light-dependent translocation of arrestin in rod photoreceptors is signaled through a phospholipase C cascade and requires ATP.

@article{Orisme2010LightdependentTO,
  title={Light-dependent translocation of arrestin in rod photoreceptors is signaled through a phospholipase C cascade and requires ATP.},
  author={Wilda Orisme and Jian Li and Tobias Goldmann and Susan N. Bolch and Uwe Wolfrum and W. Clay Smith},
  journal={Cellular signalling},
  year={2010},
  volume={22 3},
  pages={
          447-56
        }
}
Partitioning of cellular components is a critical mechanism by which cells can regulate their activity. In rod photoreceptors, light induces a large-scale translocation of arrestin from the inner segments to the outer segments. The purpose of this project is to elucidate the signaling pathway necessary to initiate arrestin translocation to the outer segments and the mechanism for arrestin translocation. Mouse retinal organotypic cultures and eyes from transgenic Xenopus tadpoles expressing a… CONTINUE READING

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