Light and electron microscopic analysis of KChIP and Kv4 localization in rat cerebellar granule cells.

@article{Strassle2005LightAE,
  title={Light and electron microscopic analysis of KChIP and Kv4 localization in rat cerebellar granule cells.},
  author={Brian W. Strassle and Milena Menegola and Kenneth J. Rhodes and James S Trimmer},
  journal={The Journal of comparative neurology},
  year={2005},
  volume={484 2},
  pages={144-55}
}
Potassium channels are key determinants of neuronal excitability. We recently identified KChIPs as a family of calcium binding proteins that coassociate and colocalize with Kv4 family potassium channels in mammalian brain (An et al. [2000] Nature 403:553). Here, we used light microscopic immunohistochemistry and multilabel immunofluorescence labeling, together with transmission electron microscopic immunohistochemistry, to examine the subcellular distribution of KChIPs and Kv4 channels in adult… CONTINUE READING