Light-absorbing properties, stability, and spectral stabilization of indocyanine green.

@article{Landsman1976LightabsorbingPS,
  title={Light-absorbing properties, stability, and spectral stabilization of indocyanine green.},
  author={M. L. J. Landsman and Gerard Kwant and Gerrit A. Mook and Willem G. Zijlstra},
  journal={Journal of applied physiology},
  year={1976},
  volume={40 4},
  pages={575-83}
}
The absorption spectrum of indocyanine green depends on the nature of the solvent medium and on the dye concentration. Binding to plasma proteins causes the principal peaks in the absorption spectrum to shift about 25 nm toward the higher wavelengths. The much greater influence on the spectrum of the dye concentration results from progressive aggregate formation with increasing concentration. Indocyanine green solutions therefore do not follow Lambert-Beer's law above 15 mg-I-1 (in plasma… CONTINUE READING

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