Light Therapy for Seasonal Affective Disorder with Blue Narrow-Band Light-Emitting Diodes (LEDs)

  title={Light Therapy for Seasonal Affective Disorder with Blue Narrow-Band Light-Emitting Diodes (LEDs)},
  author={G. Glickman and B. Byrne and C. Pineda and W. Hauck and G. Brainard},
  journal={Biological Psychiatry},
  • G. Glickman, B. Byrne, +2 authors G. Brainard
  • Published 2006
  • Materials Science, Medicine
  • Biological Psychiatry
  • BACKGROUND While light has proven an effective treatment for Seasonal Affective Disorder (SAD), an optimal wavelength combination has not been determined. Short wavelength light (blue) has demonstrated potency as a stimulus for acute melatonin suppression and circadian phase shifting. METHODS This study tested the efficacy of short wavelength light therapy for SAD. Blue light emitting diode (LED) units produced 468 nm light at 607 microW/cm2 (27 nm half-peak bandwidth); dim red LED units… CONTINUE READING
    190 Citations

    Paper Mentions

    Interventional Clinical Trial
    The specific aim of this study is to test the hypothesis that light stimuli concentrated around 467 nm will evoke a significantly stronger therapeutic response in SAD patients… Expand
    ConditionsSeasonal Affective Disorder
    Are short (blue) wavelengths necessary for light treatment of seasonal affective disorder?
    • 11
    • Highly Influenced
    Red white and blue – bright light effects in a diurnal rodent model for seasonal affective disorder
    • 4
    • Highly Influenced
    Narrow‐band blue‐light treatment of seasonal affective disorder in adults and the influence of additional nonseasonal symptoms
    • 59
    • Highly Influenced
    Blue light from light-emitting diodes elicits a dose-dependent suppression of melatonin in humans.
    • 177
    • PDF


    Ultraviolet versus non-ultraviolet light therapy for seasonal affective disorder.
    • 41
    Treatment of seasonal affective disorder with green light and red light.
    • 72
    Bright light treatment of winter depression: a placebo-controlled trial.
    • 333
    • PDF
    Bright light therapy: side effects and benefits across the symptom spectrum.
    • 124
    Differential effects of light wavelength in phase advancing the melatonin rhythm
    • 136
    • PDF
    Side effects induced by bright light treatment for seasonal affective disorder.
    • 85
    A controlled trial of timed bright light and negative air ionization for treatment of winter depression.
    • 305
    • PDF
    Bright light therapy in focus: lamp emission spectra and ocular safety.
    • 51
    Morning vs evening light treatment of patients with winter depression.
    • 312
    • PDF
    Circadian time of morning light administration and therapeutic response in winter depression.
    • 312
    • PDF