Light-Dependent Translocation of Visual Arrestin Regulated by the NINAC Myosin III

@article{Lee2004LightDependentTO,
  title={Light-Dependent Translocation of Visual Arrestin Regulated by the NINAC Myosin III},
  author={Seung-Jae Lee and Craig T. Montell},
  journal={Neuron},
  year={2004},
  volume={43},
  pages={95-103}
}
The rhodopsin regulatory protein, visual arrestin, undergoes light-dependent trafficking in mammalian and Drosophila photoreceptor cells, though the mechanisms underlying these movements are poorly understood. In Drosophila, the movement of the visual arrestin, Arr2, functions in long-term adaptation and is dependent on interaction with phosphoinositides (PIs). However, the basis for the requirement for PIs for light-dependent shuttling was unclear. Here, we demonstrated that the dynamic… CONTINUE READING

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