Light Activates Output from Evening Neurons and Inhibits Output from Morning Neurons in the Drosophila Circadian Clock

@article{Picot2007LightAO,
  title={Light Activates Output from Evening Neurons and Inhibits Output from Morning Neurons in the Drosophila Circadian Clock},
  author={Marie Christine Picot and Paola Cusumano and Andr{\'e} Klarsfeld and Ryu Ueda and François Rouyer},
  journal={PLoS Biology},
  year={2007},
  volume={5},
  pages={333 - 335}
}
Animal circadian clocks are based on multiple oscillators whose interactions allow the daily control of complex behaviors. The Drosophila brain contains a circadian clock that controls rest-activity rhythms and relies upon different groups of PERIOD (PER)-expressing neurons. Two distinct oscillators have been functionally characterized under light-dark cycles. Lateral neurons (LNs) that express the pigment-dispersing factor (PDF) drive morning activity, whereas PDF-negative LNs are required for… CONTINUE READING
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