Ligands for L-selectin: homing, inflammation, and beyond.

@article{Rosen2004LigandsFL,
  title={Ligands for L-selectin: homing, inflammation, and beyond.},
  author={S D Rosen},
  journal={Annual review of immunology},
  year={2004},
  volume={22},
  pages={
          129-56
        }
}
Understanding the molecular basis of lymphocyte homing to lymphoid organs was originally a problem of concern only to immunologists. With the discovery of L-selectin and its ligands, interested scientists have expanded to include glycobiologists, immunopathologists, cancer biologists, and developmental biologists. Going beyond its first discovered role in homing to lymph nodes, the L-selectin system is implicated in such diverse processes as inflammatory leukocyte trafficking in both acute and… CONTINUE READING
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