Ligand-responsive transcriptional regulation by members of the MarR family of winged helix proteins.

  title={Ligand-responsive transcriptional regulation by members of the MarR family of winged helix proteins.},
  author={Steven P Wilkinson and Anne Grove},
  journal={Current issues in molecular biology},
  volume={8 1},
The MarR (multiple antibiotic resistance regulator) family of prokaryotic transcriptional regulators includes proteins critical for control of virulence factor production, bacterial response to antibiotic and oxidative stresses and catabolism of environmental aromatic compounds. Recognition of the adaptive cellular responses mediated by MarR homologs, and the clinical isolation of antibiotic-resistant bacterial strains harboring MarR mutations, has garnered increasing medical and agricultural… CONTINUE READING


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