Ligand-regulated internalization and recycling of human beta 2-adrenergic receptors between the plasma membrane and endosomes containing transferrin receptors.

@article{Zastrow1992LigandregulatedIA,
  title={Ligand-regulated internalization and recycling of human beta 2-adrenergic receptors between the plasma membrane and endosomes containing transferrin receptors.},
  author={Mark von Zastrow and Brian K. Kobilka},
  journal={The Journal of biological chemistry},
  year={1992},
  volume={267 5},
  pages={3530-8}
}
Agonist-regulated redistribution of human beta 2-adrenergic receptors was examined in 293 cells. A specific antiserum recognizing the carboxyl-terminal hydrophilic domain of the receptor was developed, characterized, and used for immunocytochemical localization of receptors in fixed cells by conventional fluorescence and confocal fluorescence microscopy… CONTINUE READING