Ligand-free palladium-catalysed direct arylation of heteroaromatics using low catalyst loadings.

@article{Pogan2008LigandfreePD,
  title={Ligand-free palladium-catalysed direct arylation of heteroaromatics using low catalyst loadings.},
  author={Franc Po{\vz}gan and Julien Roger and Henri Doucet},
  journal={ChemSusChem},
  year={2008},
  volume={1 5},
  pages={
          404-7
        }
}
The arylation of heteroaromatics is an important field for research in organic synthesis. Palladium-catalysed Suzuki, Negishi or Stille cross-couplings are among the most important methods to perform such reactions. However, they require the preparation of an organometallic derivative and lead to the production of an organometallic salt (MX) as by-product. In 1990, Ohta et al. reported the direct arylation of thiophenes, furans or thiazoles with aryl halides through C H bond activation in… 
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