Ligand-Targeted Drug Delivery.

@article{Srinivasarao2017LigandTargetedDD,
  title={Ligand-Targeted Drug Delivery.},
  author={Madduri Srinivasarao and Philip S Low},
  journal={Chemical reviews},
  year={2017},
  volume={117 19},
  pages={
          12133-12164
        }
}
Safety and efficacy constitute the major criteria governing regulatory approval of any new drug. The best method to maximize safety and efficacy is to deliver a proven therapeutic agent with a targeting ligand that exhibits little affinity for healthy cells but high affinity for pathologic cells. The probability of regulatory approval can conceivably be further enhanced by exploiting the same targeting ligand, conjugated to an imaging agent, to select patients whose diseased tissues display… CONTINUE READING
BETA
5
Twitter Mentions

Citations

Publications citing this paper.
SHOWING 1-10 OF 10 CITATIONS

Current Strategies and Applications for Precision Drug Design

  • Front. Pharmacol.
  • 2018
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 231 REFERENCES

Similar Papers

Loading similar papers…