Ligand-Based Virtual Screening Approach Using a New Scoring Function

@article{Hamza2012LigandBasedVS,
  title={Ligand-Based Virtual Screening Approach Using a New Scoring Function},
  author={Adel Hamza and Ning-Ning Wei and Chang-Guo Zhan},
  journal={Journal of chemical information and modeling},
  year={2012},
  volume={52 4},
  pages={963-74}
}
In this study, we aimed to develop a new ligand-based virtual screening approach using an effective shape-overlapping procedure and a more robust scoring function (denoted by the HWZ score for convenience). The HWZ score-based virtual screening approach was tested against the compounds for 40 protein targets available in the Database of Useful Decoys (DUD; dud.docking.org/jahn/ ), and the virtual screening performance was evaluated in terms of the area under the receiver operator characteristic… CONTINUE READING

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low-frequency normal modes for refinement of homology models: Application to H3 antagonists

  • K. Palczewski, T. Kumasaka, T. Hori, C. Behnke
  • Proteins−Struct. Funct. Bioinf. 2010,
  • 2010

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