Lifetime of plasma cells in the bone marrow

@article{Manz1997LifetimeOP,
  title={Lifetime of plasma cells in the bone marrow},
  author={R. Manz and A. Thiel and Andreas Radbruch},
  journal={Nature},
  year={1997},
  volume={388},
  pages={133-134}
}
Immune protection is based on long-lived memory cells and effector cells, which are either cytotoxic or secrete antibodies. The lifespan of these effector cells has not so far been determined. Here we show that antibody-secreting plasma cells from bone marrow are as long-lived as memory B cells. 
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