Lifespan extension in Caenorhabditis elegans by complete removal of food.

  title={Lifespan extension in Caenorhabditis elegans by complete removal of food.},
  author={Tammi L Kaeberlein and Erica D. Smith and Mitsuhiro Tsuchiya and K Linnea Welton and James Harold Thomas and Stanley Fields and Brian Kennedy and Matt Kaeberlein},
  journal={Aging cell},
  volume={5 6},
A partial reduction in food intake has been found to increase lifespan in many different organisms. We report here a new dietary restriction regimen in the nematode Caenorhabditis elegans, based on the standard agar plate lifespan assay, in which adult worms are maintained in the absence of a bacterial food source. These findings represent the first report in any organism of lifespan extension in response to prolonged starvation. Removal of bacterial food increases lifespan to a greater extent… CONTINUE READING
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