Lifelong ethanol consumption and loss of locus coeruleus neurons in AA and ANA rats.

@article{Rintala1998LifelongEC,
  title={Lifelong ethanol consumption and loss of locus coeruleus neurons in AA and ANA rats.},
  author={Jyrki Rintala and Pia Jaatinen and Li Wei and Maija Sarviharju and Per Eriksson and Kalervo Kiianmaa and Antti Hervonen},
  journal={Alcohol},
  year={1998},
  volume={16 3},
  pages={243-8}
}
The effects of lifelong ethanol exposure and aging on the morphology of the locus coeruleus (LC) were studied in the AA (Alko, Alcohol) and ANA (Alko, Nonalcohol) rats of both sexes. The ethanol-consuming (EtOH) rats were given 12% (v/v) ethanol as the only drinking fluid from 4 to 22 months of age, whereas the young (3-month-old) and aged (24-month-old) controls had only water available. The total LC neuron numbers were obtained by using the unbiased disector method. In the AA line, as we have… CONTINUE READING