Life with CO or CO2 and H2 as a source of carbon and energy

@article{Wood1991LifeWC,
  title={Life with CO or CO2 and H2 as a source of carbon and energy},
  author={H G Wood},
  journal={The FASEB Journal},
  year={1991},
  volume={5},
  pages={156 - 163}
}
  • H. Wood
  • Published 1 February 1991
  • Chemistry, Medicine
  • The FASEB Journal
An account is presented of the recent discovery of a pathway of growth by bacteria in which CO or CO2 and H2 are sources of carbon and energy. The Calvin cycle and subsequently other cycles were discovered in the 1950s, and in each the initial reaction of CO2 involved adding CO2 to an organic compound formed during the cyclic pathway (for example, CO2 and ribulose diphosphate). Studies were initiated in the 1950s with the thermophylic anaerobic organism Clostridium thermoaccticum, which Barker… Expand
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The utilization of carbon monoxide as energy and/or carbon source by different physiological groups of bacteria is described and compared and the little information available on the nutritional and physicochemical requirements determining the sink strength is summarized. Expand
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  • Chemistry, Medicine
  • Frontiers in Microbiology
  • 2020
TLDR
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Homoacetogenic bacteria are strictly anaerobic microorganisms that catalyze the formation of acetate from C1 units in their energy metabolism. Most of these organisms are able to grow at the expense… Expand
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TLDR
The functional transfer of CO utilization between Thermococcus and Pyrococcus species demonstrated herein is representative of the horizontal gene transfer of an environmentally relevant metabolic capability. Expand
Carbon monoxide-dependent energy metabolism in anaerobic bacteria and archaea
TLDR
Recent insights into the CO-dependent physiology of anaerobic microorganisms with a focus on methanogenic archaea are summarized and Methanosarcina acetivorans, thought to strictly rely on the process of methanogenesis, exemplifies how the beneficial redox properties of CO can be exploited in unexpected ways by anaerobia microorganisms. Expand
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TLDR
The central carbon metabolism of all organisms is considered to follow a well established fixed scheme, but recent studies of autotrophic carbon fixation in prokaryotes revealed unfamiliar metabolic links that may provide useful tools for metabolic engineering. Expand
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TLDR
Different lines of evidence, including experimental reports on the NiS/FeS-mediated C-C bond formation from CO and CH3SH are used here to argue that the first CO2-fixation route may have been a semi-enzymatic Wood-like pathway. Expand
Alternative pathways of carbon dioxide fixation: insights into the early evolution of life?
  • G. Fuchs
  • Biology, Medicine
  • Annual review of microbiology
  • 2011
TLDR
Five alternative autotrophic pathways exist in prokaryotes that differ fundamentally from the Calvin-Benson cycle and reveal that the formation of an activated acetic acid from inorganic carbon represents the initial step toward metabolism. Expand
Reaction engineering analysis of the autotrophic energy metabolism of Clostridium aceticum
TLDR
The addition of the Na+‐selective ionophore ETH2120 or the protonophore CCCP or the H+/cation‐antiporter monensin revealed that an H+ gradient is used as primary energy conservation mechanism, which strengthens the exceptional position of C. aceticum as acetogenic bacterium showing an H+. Expand
Carbon monoxide conversion with Clostridium aceticum
TLDR
Analysis of the autotrophic potential revealed that the first isolated acetogenic bacterium Clostridium aceticum was able to use CO as sole carbon and energy source for chemolithoautotrophic carbon fixation but simultaneously showed little tolerance to high CO concentrations. Expand
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References

SHOWING 1-10 OF 61 REFERENCES
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TLDR
Emphasis is placed upon the acetyl CoA pathway in acetogenic bacteria, but important advances in the study of other strict anaerobes are also considered. Expand
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An enzyme from Clostridium thermoaceticum has been isolated which reduces disulfides of carbon monoxide dehydrogenase and it has been named CO dehydrogenase disulfide reductase. The enzyme is a… Expand
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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