Life stressors and 5-HTTLPR interaction in relation to midpregnancy depressive symptoms among African-American women.

@article{Scheid2011LifeSA,
  title={Life stressors and 5-HTTLPR interaction in relation to midpregnancy depressive symptoms among African-American women.},
  author={Jeanette M Scheid and Claudia B Holzman and Nicole Jones and Karen H. Friderici and Katherine A. Jernigan and Laura L. Symonds and Alla Sikorskii and R Danielle Fisher},
  journal={Psychiatric genetics},
  year={2011},
  volume={21 6},
  pages={271-80}
}
OBJECTIVE In earlier analyses of nonHispanic White women we found a stronger relation between abuse history and midpregnancy elevated depressive symptoms in women with the serotonin transporter (5-HTTLPR) S/S genotype. Here, we focus on African-American women (N=698). Our inquiry is motivated by racial differences in depression diagnosis/treatment, stressors, and frequency of major 5-HTTLPR alleles (S, LA, LG). MATERIALS AND METHODS Stressful life events (lifetime) and depressive symptoms… CONTINUE READING