Life spans and senescent phenotypes in two strains of Zebrafish (Danio rerio)

@article{Gerhard2002LifeSA,
  title={Life spans and senescent phenotypes in two strains of Zebrafish (Danio rerio)},
  author={G. Gerhard and E. J. Kauffman and Xujun Wang and Richard Stewart and K. Cheng},
  journal={Experimental Gerontology},
  year={2002},
  volume={37},
  pages={1055-1068}
}
Zebrafish have become a widely used model organism in developmental biology research. In order to initiate an experimental foundation for aging studies, we have determined some basic gerontological parameters for populations of outbred zebrafish, and the golden sparse strain. Outbred zebrafish manifested a mean life span of about 42 months, with the longest living individual surviving for 66 months. The golden sparse populations had a mean life span of 36 months and a maximum longevity of 58… Expand
202 Citations
A call to fins! Zebrafish as a gerontological model
  • 58
Zebrafish as Aging Models
  • 6
Functional Aging and Gradual Senescence in Zebrafish
  • S. Kishi
  • Biology, Medicine
  • Annals of the New York Academy of Sciences
  • 2004
  • 78
Comparative aspects of zebrafish (Danio rerio) as a model for aging research
  • G. Gerhard
  • Biology, Medicine
  • Experimental Gerontology
  • 2003
  • 79
  • PDF
The zebrafish as a vertebrate model of functional aging and very gradual senescence
  • 157
  • Highly Influenced
  • PDF
The use of mature zebrafish (Danio rerio) as a model for human aging and disease.
  • E. Keller, J. Murtha
  • Biology, Medicine
  • Comparative biochemistry and physiology. Toxicology & pharmacology : CBP
  • 2004
  • 102
Embryonic Senescence and Laminopathies in a Progeroid Zebrafish Model
  • 40
  • PDF
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 42 REFERENCES
Ageing in fishes.
  • 85
  • Highly Influential
Longevity, senescence, and the genome
  • 1,148
Ethylnitrosourea Induces Neoplasia in Zebrafish (Danio rerio)
  • 87
  • PDF
Genetic dissection of vertebrate processes in the zebrafish: a comparison of uniparental and two-generation screens.
  • K. Cheng, J. L. Moore
  • Biology, Medicine
  • Biochemistry and cell biology = Biochimie et biologie cellulaire
  • 1997
  • 27
Biodemographic trajectories of longevity.
  • 949
  • PDF
The evolution of senescence in natural populations of guppies (Poecilia reticulata): a comparative approach
  • 70
Zebrafish Earns Its Stripes in Genetic Screens
  • 30
A genetic screen for mutations affecting embryogenesis in zebrafish.
  • 1,288
  • PDF
Age at sexual maturity and its relationship to longevity in the male annual cyprinodont fish, Nothobranchius guenther.
  • 38
Effective targeted gene ‘knockdown’ in zebrafish
  • 2,469
...
1
2
3
4
5
...