Life-span dendritic and spine changes in areas 10 and 18 of human cortex: a quantitative Golgi study.

@article{Jacobs1997LifespanDA,
  title={Life-span dendritic and spine changes in areas 10 and 18 of human cortex: a quantitative Golgi study.},
  author={Bob Jacobs and L Driscoll and Matthew Schall},
  journal={The Journal of comparative neurology},
  year={1997},
  volume={386 4},
  pages={
          661-80
        }
}
Dendritic neuropil is a sensitive indicator of the aging process and may exhibit regional cortical variations. The present study examined regional differences and age-related changes in the basilar dendrites/spines of supragranular pyramidal cells in human prefrontal (area 10) and secondary occipital (area 18) cortices. Tissue was obtained from the left hemisphere of 26 neurologically normal individuals ranging in age from 14 to 106 years (M(age) = 57 +/- 22 years; 13 males, 13 females). In… CONTINUE READING

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