Life-space constriction, development of frailty, and the competing risk of mortality: the Women's Health And Aging Study I.

@article{Xue2008LifespaceCD,
  title={Life-space constriction, development of frailty, and the competing risk of mortality: the Women's Health And Aging Study I.},
  author={Qian-Li Xue and Linda P. Fried and Thomas Glass and Alison M. Laffan and Paulo H M Chaves},
  journal={American journal of epidemiology},
  year={2008},
  volume={167 2},
  pages={240-8}
}
Frailty is a common clinical syndrome in older adults that carries an increased risk for poor health outcomes. Little is known about the behavioral antecedents of frailty. In this study, the authors hypothesized that constriction of life space identifies older adults at risk for frailty, potentially a marker of already-decreased physiologic reserve. The authors analyzed the 3-year (1992-1995) cumulative incidence of frailty using a previously validated clinical phenotype in relation to baseline… CONTINUE READING

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