Life-science applications of the Cambridge Structural Database.

@article{Taylor2002LifescienceAO,
  title={Life-science applications of the Cambridge Structural Database.},
  author={Robin James Taylor},
  journal={Acta crystallographica. Section D, Biological crystallography},
  year={2002},
  volume={58 Pt 6  No 1},
  pages={879-88}
}
Several studies show that the molecular geometries and intermolecular interactions observed in small-molecule crystal structures are relevant to the modelling of in vivo situations, although the influence of crystal packing is sometimes important and should always be borne in mind. Torsional distributions derived from the Cambridge Structural Database (CSD) can be used to map out potential-energy surfaces and thereby help identify experimentally validated conformational minima of molecules with… CONTINUE READING

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References

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Adv

  • J. P. Glusker
  • Protein Chem. 42, 1±76.
  • 1991
Highly Influential
4 Excerpts

Acta Cryst

  • M. M. Harding
  • D55, 1432±1443.
  • 1999

Rational Drug Design, edited

  • G. Jones, P. Willett, R. C. Glen, A. R. Leach, R. Taylor
  • 1999
2 Excerpts

Structure-Based Ligand Design, edited

  • E. A. Lunney, C. Humblet
  • 1998
1 Excerpt

The Hydrophobic Effect, 2nd ed

  • M. J. 12207±12217. Sippl
  • Curr. Opin. Struct. Biol
  • 1995
1 Excerpt

Chem

  • C. A. Hunter
  • Rev. 94, 101±109.
  • 1994
1 Excerpt

DGEOM. Distance Geometry Program

  • J. M. Blaney, G. M. Crippen, A. Dearing, J. S. Dixon
  • QCPE Program No. 590
  • 1990
1 Excerpt

SCA. Systematic Conformational Analysis

  • J. Ho ̄ack, P. J. DeClercq, S. Cauwberghs
  • QCPE Program No. QCMP079
  • 1989
1 Excerpt

Applications of Arti®cial

  • W. T. Submitted. Wipke, M. A. Hahn
  • 1986
2 Excerpts

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