Life expectancy, antagonistic pleiotropy, and the testis of dogs and men.

@article{Waters2000LifeEA,
  title={Life expectancy, antagonistic pleiotropy, and the testis of dogs and men.},
  author={David J. Waters and Shuren Shen and Larry T. Glickman},
  journal={The Prostate},
  year={2000},
  volume={43 4},
  pages={272-7}
}
BACKGROUND Prostate cancer and benign prostatic hyperplasia are important age-related prostatic diseases that are under the influence of testicular hormones. However, the disparity between male and female life expectancy within the human population cannot be explained solely by the prevalence of prostatic disease-related mortality. The purpose of this paper is to explore the possibility that the testis exerts a detrimental effect on life span. METHODS First, we review previously published and… CONTINUE READING

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