Life at the beginning: perturbation of the microbiota by antibiotics in early life and its role in health and disease

@article{Zeissig2014LifeAT,
  title={Life at the beginning: perturbation of the microbiota by antibiotics in early life and its role in health and disease},
  author={Sebastian Zeissig and Richard S Blumberg},
  journal={Nature Immunology},
  year={2014},
  volume={15},
  pages={307-310}
}
Upon delivery, neonates leave a sterile environment and are rapidly exposed to and colonized by so-called ‘pioneer’ organisms whose composition is determined by the type of delivery7–9. Thus, vaginal delivery is associated with neonatal colonization by microorganisms dominant in the vaginal tract and feces of the mother, while delivery by Cesarean section leads to a different set of pioneer organisms acquired mainly from microbial communities that colonize the skin of caregivers7–9. The latter… CONTINUE READING

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