Life and death with arsenic. Arsenic life: an analysis of the recent report "A bacterium that can grow by using arsenic instead of phosphorus".

@article{Rosen2011LifeAD,
  title={Life and death with arsenic. Arsenic life: an analysis of the recent report "A bacterium that can grow by using arsenic instead of phosphorus".},
  author={Barry P. Rosen and A. Abdul Ajees and Timothy R McDermott},
  journal={BioEssays : news and reviews in molecular, cellular and developmental biology},
  year={2011},
  volume={33 5},
  pages={350-7}
}
Arsenic and phosphorus are group 15 elements with similar chemical properties. Is it possible that arsenate could replace phosphate in some of the chemicals that are required for life? Phosphate esters are ubiquitous in biomolecules and are essential for life, from the sugar phosphates of intermediary metabolism to ATP to phospholipids to the phosphate backbone of DNA and RNA. Some enzymes that form phosphate esters catalyze the formation of arsenate esters. Arsenate esters hydrolyze very… CONTINUE READING

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