Life and death of neurons in the aging brain.

@article{Morrison1997LifeAD,
  title={Life and death of neurons in the aging brain.},
  author={John Morrison and Patrick R. Hof},
  journal={Science},
  year={1997},
  volume={278 5337},
  pages={
          412-9
        }
}
Neurodegenerative disorders are characterized by extensive neuron death that leads to functional decline, but the neurobiological correlates of functional decline in normal aging are less well defined. For decades, it has been a commonly held notion that widespread neuron death in the neocortex and hippocampus is an inevitable concomitant of brain aging, but recent quantitative studies suggest that neuron death is restricted in normal aging and unlikely to account for age-related impairment of… CONTINUE READING
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