Life and death in the microcirculation: a role for angiotensin II.

@article{Greene1998LifeAD,
  title={Life and death in the microcirculation: a role for angiotensin II.},
  author={Andrew S. Greene},
  journal={Microcirculation},
  year={1998},
  volume={5 2-3},
  pages={101-7}
}
OBJECTIVE Angiotensin II (ANGII) plays a critical role in the maintenance of the microcirculation and in the anatomical loss of microvessels (rarefaction) that occurs in low renin forms of hypertension and in animals fed a high-salt diet. Elevations in sodium intake can trigger a series of hemodynamic and hormonal responses culminating in a substantial rarefaction of small arterioles and capillaries in both normal and reduced renal mass hypertensive rats. METHODS Immunohistochemistry… CONTINUE READING
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