Life after death: the critical role of extracellular DNA in microbial biofilms

@article{Jakubovics2013LifeAD,
  title={Life after death: the critical role of extracellular DNA in microbial biofilms},
  author={Nicholas Stephen Jakubovics and Robert C. Shields and Nithyalakshmy Rajarajan and J. Grant Burgess},
  journal={Letters in Applied Microbiology},
  year={2013},
  volume={57}
}
The death and lysis of microbial cells leads to the release of cytoplasmic contents, many of which are rapidly degraded by enzymes. However, some macromolecules survive intact and find new functions in the extracellular environment. There is now strong evidence that DNA released from cells during lysis, or sometimes by active secretion, becomes a key component of the macromolecular scaffold in many different biofilms. Enzymatic degradation of extracellular DNA can weaken the biofilm structure… 
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