Life after death: Controlling autoreactive CD8+ T-cell responses

Abstract

There have been numerous reports of the development of autoantibodies, as well as autoimmune CD4 and/or CD8 T-cell responses, during infection, but the molecular mechanisms controlling these responses to self constituents remain unclear and controversial. Immune recognition by CD8 T cells requires that the antigen receptor on the T cells recognize non… (More)
DOI: 10.1038/89886

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