Life-Threatening Constipation Associated with Clozapine

  title={Life-Threatening Constipation Associated with Clozapine},
  author={Sanil Rege and Tim Lafferty},
  journal={Australasian Psychiatry},
  pages={216 - 219}
Objective: The aim of this paper was to describe the association of clozapine with life-threatening constipation. Method: Case report. Results: A 53-year-old man presented to the emergency department with severe abdominal pain and bilious vomiting after being on clozapine for over a year for schizoaffective disorder. Surgery revealed severe faecal impaction in the large and small bowel. Clozapine was ceased. There were significant difficulties in the subsequent psychiatric management. Clozapine… 

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