Life Span Extension Research and Public Debate: Societal Considerations

  title={Life Span Extension Research and Public Debate: Societal Considerations},
  author={Aubrey D N J de Grey},
  journal={Studies in Ethics, Law, and Technology},
  • A. D. de Grey
  • Published 2007
  • Psychology
  • Studies in Ethics, Law, and Technology
The pace of a given strand of scientific research, whether purely curiosity-driven or motivated by a particular technological goal, is strongly influenced by public attitudes towards its value. In the case of research directed to the radical postponement of aging and the consequent extension of healthy and total lifespans, public opinion is entrenched in a "pro-aging trance" a state of resolute irrationality. This arises from the entirely rational attitude to a grisly, inevitable and relatively… 
4 Citations
Cranberry Powder Attenuates Benign Prostatic Hyperplasia in Rats.
Results indicate that CR could attenuate BPH by inhibiting 5-alpha reductase and by reducing other biomarkers such as prostate weight and DHT levels, and CR may be an effective candidate for the development of a functional food for BPH treatment.
Artificial intelligence in longevity medicine
How recent applications of AI to aging research are leading to the emergence of the field of longevity medicine is discussed.
Business issues


Life extension, human rights, and the rational refinement of repugnance
It is concluded that the present caution concerning the wisdom of truly curing ageing is likely to survive the increased scrutiny that it will receive in coming years as a result of technical advances, and will not, because of its irreconcilability with values that are more deeply held by the large majority of humanity than any values that argue against the quest for a cure.
Calorie restriction, post-reproductive life span, and programmed aging: a plea for rigor.
: All scientists are acutely aware of the profound challenge that they face when communicating scientific findings to nonscientists, especially when great uncertainty is involved and when the topic
The foreseeability of real anti-aging medicine: focusing the debate.
A survey is made of the more conspicuously flawed arguments suggesting tremendous difficulties or dangers in developing such interventions, to tow those arguments firmly out into the ocean and give them the decent but unambiguous public burial that they so richly deserve.
Biogerontologists' duty to discuss timescales publicly.
  • A. D. de Grey
  • Medicine
    Annals of the New York Academy of Sciences
  • 2004
It is argued here that the prevalence of this outright irrationality is largely the fault of gerontologists themselves, and the potential to delay the development of rejuvenation therapies by denying them the funding that would be forthcoming if society had greater optimism concerning their foreseeability.
Pursuing the Longevity Dividend
It is argued that the social, economic, and health benefits that would result from such advances may be thought of as “longevity dividends,” and that they should be aggressively pursued as the new approach to health promotion and disease prevention in the 21st century.
A strategy for postponing aging indefinitely.
  • A. D. de Grey
  • Medicine
    Studies in health technology and informatics
  • 2005
It is reasonable to expect that therapies that can add 30 healthy years to the remaining lifespan of healthy 55-year-olds will arrive within the next few decades and those who benefit from those therapies will very probably continue to benefit from progressively improved therapies indefinitely and thus avoid debilitation or death from age-related causes at any age.
Like it or not, life-extension research extends beyond biogerontology.
In this issue of EMBO reports, Warner and 27 other biogerontologists dismiss strategies for engineered negligible senescence (SENS) as ‘scientifically’ unrealistic (Warner et al, 2005); like Kelvin, they forget that engineering differs profoundly from science in its goals, methods and skills.
Time to Talk SENS: Critiquing the Immutability of Human Aging
This work surveys the major categories of damage and the ways in which, with current or foreseeable biotechnology, they could be reversed, implying that indefinite postponement of aging—which is termed “engineered negligible senescence”—may be within sight.
What should we be doing to prepare for the unprecedented aging of humanity ?
It is suggested that a concerted effort to slow aging begin immediately – because it will save and extend lives, improve health, and create wealth.
In pursuit of the longevity dividend
It is suggested that a concerted effort to slow aging begin immediately - because it will save and extend lives, improve health, and create wealth.