Life Extension by Calorie Restriction in Humans

@article{Everitt2007LifeEB,
  title={Life Extension by Calorie Restriction in Humans},
  author={Arthur V. Everitt and David G. Le Couteur},
  journal={Annals of the New York Academy of Sciences},
  year={2007},
  volume={1114}
}
Abstract:  Long‐term reduction in energy intake in the diet (calorie restriction [CR]) extends the life of the laboratory rat by about 25%. However, in humans there are no life‐long studies of CR, but only short‐term trials which indicate that 20% CR acting over periods of 2–6 years is associated with reduced body weight, blood pressure, blood cholesterol, and blood glucose—risk factors for the major killer diseases of cardiovascular disease and diabetes. In addition, recent research has shown… 
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