Life‐span Studies on Spontaneous Tumor Development in the Medaka (Oryzias latipes)

@inproceedings{Masahito1989LifespanSO,
  title={Life‐span Studies on Spontaneous Tumor Development in the Medaka (Oryzias latipes)},
  author={Prince Masahito and Kazuko Aoki and Nobuo Egami and Takatoshi Ishikawa and Haruo Sugano},
  booktitle={Japanese journal of cancer research : Gann},
  year={1989}
}
A total of 961 medaka, separated chronologically from the first to the fifth year of life, were examined for spontaneous tumor development. While no liver tumors were found in either male or female medaka under the age of 1 year and the incidence in 2-year-old fish was relatively low (males 1.9% and females 1.7%), they became more common with advancing age. The incidence was higher in females than in males from 3 to 5 years of age, reaching 7.1% in 5-year-old female stock. These liver tumors… CONTINUE READING
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