Life‐Threatening Bradyarrhythmia After Massive Azithromycin Overdose

  title={Life‐Threatening Bradyarrhythmia After Massive Azithromycin Overdose},
  author={J. Tilelli and K. M. Smith and R. Pettignano},
  journal={Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy},
  • J. Tilelli, K. M. Smith, R. Pettignano
  • Published 2006
  • Medicine
  • Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
  • A 9‐month‐old infant was inadvertently administered azithromycin 50 mg/kg, taken from floor stock, instead of the prescribed ceftriaxone. Shortly thereafter, she became unresponsive and pulseless. The initial heart rhythm observed when cardiopulmonary resuscitation was started was a wide‐complex bradycardia, with a prolonged rate‐corrected QT interval and complete heart block. The baby was resuscitated with epinephrine and atropine, but she suffered severe anoxic encephalopathy. Torsade de… CONTINUE READING
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