Lidocaine-prilocaine patch decreases the pain associated with the subcutaneous administration of measles-mumps-rubella vaccine but does not adversely affect the antibody response.

@article{Halperin2000LidocaineprilocainePD,
  title={Lidocaine-prilocaine patch decreases the pain associated with the subcutaneous administration of measles-mumps-rubella vaccine but does not adversely affect the antibody response.},
  author={Scott Alan Halperin and Patrick McGrath and Bruce Smith and T M Barratt J M Beattie Janet Coleman J S Dossetor E Houston},
  journal={The Journal of pediatrics},
  year={2000},
  volume={136 6},
  pages={789-94}
}
BACKGROUND Topical lidocaine 2.5% and prilocaine 2.5% (EMLA) is effective in decreasing the pain associated with minor procedures including immunization, although the effect on the antibody response to vaccine constituents has not been assessed. OBJECTIVE To measure the antibody response to measles-mumps-rubella (MMR) vaccine, as well as pain reduction associated with the use of the EMLA patch. PARTICIPANTS AND SETTING One hundred sixty healthy infants at least 12 months old undergoing… CONTINUE READING
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