Lidocaine levels during CPR: differences after peripheral venous, central venous, and intracardiac injections.

@article{Barsan1981LidocaineLD,
  title={Lidocaine levels during CPR: differences after peripheral venous, central venous, and intracardiac injections.},
  author={William G. Barsan and Robert C. Levy and Hannah K Weir},
  journal={Annals of emergency medicine},
  year={1981},
  volume={10 2},
  pages={73-8}
}
Drug administration via peripheral vein, central vein, and intracardiac routes is generally assumed to be equally effective during cardiopulmonary resuscitation (CPR). Experiments were performed in an animal model to evaluate this assumption. Twelve mongrel dogs weighing greater than 20 kg were studied. Arterial blood pressure and electrocardiogram were monitored continuously. Cardiac outputs were evaluated before CPR to determine control. After thoracotomy and fibrillation of the heart… CONTINUE READING