Lidocaine accelerates neuroelectrical recovery after incomplete global ischemia in rabbits.

@article{Rasool1990LidocaineAN,
  title={Lidocaine accelerates neuroelectrical recovery after incomplete global ischemia in rabbits.},
  author={Najeeb Rasool and Muzaffar Faroqui and Eduardo H Rubinstein},
  journal={Stroke},
  year={1990},
  volume={21 6},
  pages={929-35}
}
The use of high-dose lidocaine for cerebral protection during ischemia has produced varied results. Our study uses a new, single carotid artery preparation in the rabbit to produce incomplete global ischemia by graded carotid occlusion; specific electroencephalographic changes are used as the end point for the extent of blood flow reduction sustained during 20 minutes. We monitored arterial pressure, intracranial pressure, and internal carotid blood flow that were recorded with an… CONTINUE READING