Lidocaine, Bupivacaine, Etidocaine, and Epinephrine‐induced Arrhythmias during Halothane Anesthesia in Dogs

@article{Chapin1980LidocaineBE,
  title={Lidocaine, Bupivacaine, Etidocaine, and Epinephrine‐induced Arrhythmias during Halothane Anesthesia in Dogs},
  author={J. C. Chapin and L. Kushins and E. Munson and L. Schick},
  journal={Anesthesiology},
  year={1980},
  volume={52},
  pages={23–26}
}
  • J. C. Chapin, L. Kushins, +1 author L. Schick
  • Published 1980
  • Medicine
  • Anesthesiology
  • Arrhythmogenic doses of epinephrine were determined in six mongrel dogs anesthetized at 1.4 MAC halothane initially in the absence of local anesthetics and then at increasing arterial plasma levels of lidocaine, bupivacaine, and etidocaine. The authors gave epinephrine intravenously at 5 μg/kg/min and calculated the arrhythmogenic dose as a function of time until two or more premature ventricular contractions occurred within a 10-sec period. The control arrythmogenic dose of epinephrine was 4… CONTINUE READING
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